产品货号：
Z32075
中文名称：
COL17A1抗体
英文名称：
Anti-COL17A1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-COL17A1 Antibody |
| 指标别名 | collagen type XVII alpha 1 chain;BA16H23.2;BP180;BPA-2;BPAG2;ERED;LAD-1;COL17A1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB,IHC,ICC/IF |
| 基因名称 | COL17A1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Collagen XVII |
| 实际分子量 | 130,180KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Collagen XVII,previously called BP180,is a transmembrane protein which plays a critical role in maintaining the linkage between the intracellular and the extracellular structural elements involved in epidermal adhesion.It is mapped to 10q25.1.This gene encodes the alpha chain of type XVII collagen.Unlike most collagens,collagen XVII is a transmembrane protein.Collagen XVII is a structural component of hemidesmosomes,multiprotein complexes at the dermal-epidermal basement membrane zone that mediate adhesion of keratinocytes to the underlying membrane.Mutations in this gene are associated with both generalized atrophic benign and junctional epidermolysis bullosa.Two homotrimeric forms of type XVII collagen exist.The full length form is the transmembrane protein.A soluble form,referred to as either ectodomain or LAD-1,is generated by proteolytic processing of the full length form. |
| Uniprot ID | Q9UMD9 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | Collagen alpha-1(XVII) chain |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:20～100 Immunocytochemistry/Immunofluorescence(ICC/IF) 1:20～100 |
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